Tirzepatide is a new class of medications being studied for the treatment of obesity. The body’s receptors for GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptor activators are activated by Tirzepatide, which is administered once per week.
Semaglutide is also a GLP-1 activator and the FDA’s most recently approved weight loss medication. The weight loss medication has been around for a while and has shown to be effective. Semaglutide is a drug that has produced incredible results for Transform You patients. Tirzepatide, the new kid in town. Here are the details.
The New England Journal of Medicine published a report on a study that used Tirzepatide as a treatment for obesity and excess body weight among adults who are not diabetic. After receiving a Tirzepatide shot once a week, participants saw measurable and sustained weight losses. The study group experienced a weight loss of 85%-91% compared to 35% in the placebo group. The 10-mg Tirzepatide group lost 50% of its members and the 15-mg group 57%. The Tirzepatide group also showed improvements in metabolic and cardiovascular measurements.
In the phase 3 SURMOUNT-1 trial, patients taking 5-mg of tirzepatide lost an average of 16% weight. The average weight loss for patients on 10 mg was 21.4% or approximately 49 pounds. The average weight loss for patients on the 15 mg dosage was 22.5% or approximately 52 pounds.
FDA approved Tirzepatide, a dual GIP/GLP-1 antagonist in May 2022. Eli Lilly has announced that the drug will be soon available in US pharmacies. Eli Lilly has now allowed Tirzepatide to be used as a weight-loss medication. The presentation took place at the 82nd Scientific Sessions of the American Diabetes Association. The presentation praised Tirzepatide’s ability to treat diabetes and obesity.
Jeff Emmick, Vice President of Product Development for Lilly Diabetes, stated that “Tirzepatide”, was the first experimental medicine to deliver more than 20% in weight loss during a phase 3 trial. This confirms our belief in its ability to help people with obesity. It is important to treat obesity effectively because it’s a chronic disease.
Tirzepatide Weight Loss Benefits
Patients who take Tirzepatide may experience:
- Substantial A1C cuts
- Weight loss is on the rise
- Improved cardiometabolic measures
- Triglycerides are higher in people with diabetes
- Appetite decrease
- Lower blood pressure
- Insulin sensitivity increases
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